trazodone 100mg pillsagainst depression

Antidepressant Trazodone 100 mg

Trazodone refers to antidepressants used for various disorders of a depressive nature. Its main difference from the classical forms of antidepressants is not its belonging to a tricyclic or tetracyclic system. The effect of the drug as a serotonin reuptake antagonist and augmenter of the parameters of neuponadachi is combined with effective blocking of receptors belonging to the 5-HT2 subtype. This explains the low risks of side effects in the sexual sphere and such consequences as increased anxiety, exacerbation of nervousness and sleep disorder, although unpleasant manifestations in the form of weakness and drowsiness are not ruled out. But the effectiveness of trazodone is inferior to a number of other antidepressants, so its use in severe forms of depression is little justified.

Trazodone user manual

Pharmachologic effect

trazodone 100mg antidepressant

Trazodone 100 mg refers to antidepressant drugs, thiazolopyridine derivatives, which have the following effects:

  • timoleptic;
  • sedative;
  • anxiolytic;
  • myorelaxing.

The main effect is manifested in the form of suppression of the reuptake of serotonin, but almost does not affect the neuronal capture of dopamine and norepinephrine. Does not have a noticeable effect on body weight, does not manifest itself in anticholinergic processes and blocking MAO.

Trazodone removes the following psychological manifestations of anxiety:

  • fear;
  • affective tension;
  • irritability;
  • sleep disorders.

It also eliminates its physical consequences:

  • headache;
  • severe sweating;
  • cardiopalmus;
  • myalgia;
  • frequent urination.

The patients normalize their sleep, the painful attraction to alcohol decreases. The drug is indicated with an abstinence syndrome, effectively blocks anxiety, so they are often completely replaced by benzodiazepines in the remission phase. There is no addiction to the drug with prolonged use, it can have a beneficial effect on the restoration of sexual functions.

In half of the patients, the therapeutic effect of trazodone becomes noticeable after a few days, and in a quarter of patients the effect is observed after 2-4 weeks of use.

Trazodone 100 mg Indications for use

Trazodone is used for the following types of disorders:

  • depression:

a) neurotic;

b) psychotic;

c) somatogenic;

d) endogenous;

  • bulimia;
  • panic attacks or phobias;
  • benzodiazepine drug dependence;
  • kleptomania;
  • acute manifestations of hangover syndrome;
  • pain in diabetic neuropathy;
  • impotence, sexual dysfunction;
  • as a prophylactic for migraine.

If the patient is diagnosed with depression, the following manifestations serve as indications for the use of the drug:

  • anxiety;
  • loss of appetite,
    insomnia;
  • inhibition or agitation;
  • weakness;
  • sexual disorders;
  • suicidal thoughts.

Trazodone: Mode of application

Trazodone is used by the prescribing doctor. The drug is most often used orally, but sometimes intravenous or intramuscular injection options are chosen. At the beginning of treatment appoint no more than 50 milligrams of the drug per day, distributed to 2-3 admission. The maximum dosage can not exceed 500 milligrams per day. With intravenous and intramuscular injection forms use one ampoule per injection.

Trazodone Side effects

When using trazodone, the following unpleasant consequences can occur:

  • sleep disorders;
  • weakness and fatigue;
  • headache and dizziness;
  • possible confusion and hallucinations;
  • an unpleasant aftertaste in the mouth, increased salivation and nausea;
  • arrhythmia, low blood pressure, tachycardia and heart failure;
  • convulsions and tremors, hypomania and muscle twitching;
  • jaundice, increased bilirubin level;
  • diarrhea or constipation, cholestasis, vomiting;
  • urticaria, pruritus, psoriasis and swelling.

Trazodone Contraindications

The drug can not be used in the following cases:

  • at an allergic reaction to its components;
  • with acute drug or alcohol intoxication;
  • pregnant women and during lactation;
  • children, if they are under 6 years old.

Care must also be taken if the patient:

  • is restored after a heart attack;
  • he has low blood pressure;
  • if there is ventricular arrhythmia;
  • suffers from liver and kidney disease;
  • if he is not 18 years old;
  • when it uses MAO inhibitors.

Overdose

Overdose of the drug is expressed in the following symptoms:

  • dizziness;
  • nausea and vomiting;
  • confused consciousness;
  • lethargy and drowsiness;
  • difficulty breathing;
  • violation of coordination of movements;
  • tremor of extremities;
  • lowering of blood pressure.

The consequences are eliminated by washing the stomach, taking absorbents, removing symptoms, supporting vital functions.

Interaction with other drugs

Trazodone 100 mg can not be used together with pseudoephedrine, their combination causes panic conditions, depersonalization, and perhaps clouding of the mind.

When combined with amiodarone, the likelihood of cardiac arrhythmia is high.

In the case of combination with trazodone, an increase in plasma concentration by the following drugs is possible:

  • Digoxin;
  • Carbamazepine;
  • Thioridazine.

It is not recommended to use a remedy with lithium salts, it can trigger a tremor, various neurotoxic effects. Joint use with alcohol is dangerous, it leads to a pronounced depression of the central nervous system.

The combination of the drug with tryptophan can manifest itself in the form of hypomania, aversion to food, psychosis. Arterial hypotension is enhanced when combined with trifluoperazine and chlorpromazine.

It is not recommended to use the medication together with phenytoin and fluoxetine to avoid side effects.

Thioridazine Composition, form of release

The active substance – trazodone hydrochloride, the drug may contain, depending on the form of release, the following auxiliaries:

  • carnauba wax;
  • sucrose;
  • povidone;
  • magnesium stearate.

Produced in the form of tablets, capsules, ampoules.

Storage conditions and conditions of leave from pharmacies

The drug refers to the drugs group B. Keep it in a place protected from light. In the pharmacy, he is released only by prescription.

Reviews of patients and doctors

The opinions of people taking trazodone are rather heterogeneous. More often, if patients used the remedy after consulting a doctor and with the dosage, it had a positive effect. Many people note the disappearance of anxiety, sleep normalization, the restoration of sexual functions, the improvement of mood, the return of efficiency.

But there are also sharply negative reviews. They report that the drug did not help in eliminating the symptoms of depression, and sometimes even aggravated them. Also, some write about a large number of side effects, among them most often are severe dizziness, weakness, nausea, dry mouth, and sleep disturbances. There are examples of the fact that the medicine had a beneficial effect, but after the end of its administration the painful manifestations returned in a stronger form.

Specialists pay attention that trazodone can be taken only after it was prescribed by the attending physician. They emphasize the importance of the correct dosage and monitoring of the patient’s well-being, especially the control of the blood and heart condition. Also, psychiatrists are unanimous in the opinion that trazodone is a specific medicine that effectively acts against a limited number of diseases, and in other cases it is useless or harmful. They also remind that there is a factor of personal intolerance of medicines, which can be established only by the attending physician.

Is it possible to order Trazodone 100 mg in foreign online pharmacies, and how to do it right?

Foreign Internet shopping is difficult for anyone to surprise. To date, you can buy everything on the Internet.

All people understand this perfectly and acquire various household items – from furniture and cars to clothes and … medicaments.

Yes-yes, you are not mistaken: today in the global network you can go even to foreign online pharmacies, in which the range of medicines is even more extensive than in the largest pharmacy in your city, and all the drugs are available.

Many consumers focus their attention on the fact that foreign online sellers offer not only a wide pharmaceutical assortment, but also lower prices. But do not immediately go to search the Internet site to buy Trazodone 100 mg. To begin with, it is important to understand that in such purchases there are pitfalls through which you must skillfully pass.

Where to buy Trazodone 100 mg online? Features of buying a medicine in an online pharmacy

People for buying drugs on the Internet are being pushed for various reasons: somebody tries to save in this way, while others simply can not buy the right medicine in domestic pharmacies because of his absence.

In fact, buying Trazodone 100 mg on the Internet is not more difficult than in a simple pharmacy, you need to go through just a few simple steps.

1. When ordering a drug Trazodone 100 mg via the Internet from you in most cases, you will not need a medical prescription.

2. Be sure to find out if the main substance of the pharmacological product has been tested in your country, and also take care of registering the drug in your country. Very often the problem of buying hides in this very moment.

3. Be sure to require from the online seller documents that confirm the quality of the products. Stumble on a fake not only in the subway, but also in foreign stores. Otherwise, all the time spent searching and buying will be lost in vain.

4. Another important point is the shelf-life of medicines and the conditions for its transportation. Some drugs should be transported at a certain temperature, and if you do not comply with these conditions, the medicine will become simply unusable.

5. If you are in a terrible situation and it is vitally important for you to get a medicine that was not previously registered in your country, but there is simply no other option, then you will have to undergo some procedure. You need to go to the Ministry of Health and issue the relevant documents for permission to import an unregistered drug. That is, the problem is solved, but it takes time.

If you walk along the Internet, you can find a considerable number of foreign online pharmacies with a good reputation for buying Trazodone 100 mg. In any case, this is an individual choice.

Order Trazodone 100 mg in online pharmacies – an advantageous business, and sometimes it is completely the only way out. Therefore, you can buy medicines in foreign online pharmacies, because even the prices there are much lower than in the usual pharmacy. And the whole point is that most drugs, before you get to the counters of pharmacies in your city, there are many intermediaries and in the end receive a considerable mark-up.

When choosing a site, be extremely careful and read the reviews well. We wish you health and successful purchases!

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